Hi Jennifer,
If you don't need to edit the text from sequencer mode and you want to preserve your styles settings that you apply in layout mode, then just click on the text object and in the Object Inspector tab labelled Template Links, uncheck the Publish Object button.
If you do want the text published, you could try adding font tags to the string in the sequencer mode. For example, if your blue font is font number 1 and your regular font is font 2, then you can do something like this in sequencer:
{1}#hashtag: {2}this is now in white..
I believe that unless you have font tags in the string, then the sequencer will make the whole line whatever font the first character in the text is.
#XPression