Yes, the CII Gateway is USB license dongle protected. You would have to move the dongle and the software.
Looking at your account it looks like you might have two CII Gateway licenses already - but the second one that shipped to you might have been because it was missed on the original order - but I can't tell. You can check what licenses are installed on the system right now:
License Reader
(Check and see if you have another XPression USB license dongle sitting inside an XPression software pack too)
Moving the CII Gateway will only cause problems if you are using it for the Studio already. Do you have any devices sending CII commands to the CII Gateway on the XPression Studio?
BlueBox does not support the CII feature of adding all CII created take items to a group, so you wouldn't be able to trigger a sequencer group with a script to play a range of take items.
With a lot of work we could get your BlueBox playing the CII created take items from ENPS stats (perhaps using Dashboard or a CII test tool) but you will have a MUCH easier and better experience if you can arrange to play your ENPS stats content from the Studio.
#XPression